AIPMT PMT Endocrine System MCQs for Medical Entrance Exams

New MCQs

1. Ca2+ level is controlled by
(a) thyroid <b) parathyroid
(c) both (a) and (b) (d) adrenal.
2. Mammalian thymus is mainly concerned with
(a) regulation of calcium level
(b) regulation of body growth
(c) immunological functions
(d) secretion of serotonin.
3. Which one of the following is proteinaceous in chemical nature?
(a) Thyroxine, adrenaline and melatonin
(b) FSH, LH (c) Progesterone
(d) Oxytocin and vasopressin
4. Which one of the following is not a catecholamine ?
(a) Dopamine (b) Epinephrine
(c) Norepinephrine (d) Serotonin
5. Which one of the following is termed temporary
(a) Pineal (b) Thymus
(c) Placenta (d) Kidney
6. Neurosecretory hormones are secreted in pars nervosa and stored in
(a) Herring bodies (b) Starling bodies
(c) carotid bodies (d) Rathke’s pouch.
7. Thyroxine and triiodothyronine, produced by the thyroid gland, are synthesized from iodine and
(a) phenylalanine (b) tyrosine
(c) tryptophan (d) cholesterol
8. The hormone acts on the same cell that produces it, is known as
(a) juxtacrine action (b) paracrine action (c) autocrine action (d) homocrine action.
9. Hormone produced in allergic reaction is
(a) nitric oxide (b) enterokinase
(c) parathormone (d) glucocorticoid
10. Mineralocorticoids are secreted from which region of adrenal cortex ?
(a) Zona glomerulosa (b) Zona fasciculata
(c) Zona reticularis (d) All of these.

Previous Exam Section Questions
1. Low Cat+ in the body fluid may be the cause of
(a) tetany (b) anaemia
(c) angina pectoris (d) gout. (AIPMT 2010)
2. A health disorder that results from the deficiency of thyroxine in adults and characterised by (i) a low metabolic rate, (ii) increase in body weight and (iii) tendency to retain water in tissues is
(a) simple goitre (b) myxoedema
(c) cretinism (d) hypothyroidism.
(AIPMT 2009)
3. Which one of the following pair of organs includes only the endocrine glands?
(a) Thymus and testes (b) Adrenal and ovary
(c) Parathyroid and adrenal
(d) Pancreas and parathyroid (AIPMT 2008)
4. Which hormone causes dilation of blood vessels, increased oxygen consumption and glucogenesis?
(a) Glucagon (b) ACTH
(c) Insulin (d) Adrenaline (AIPMT 2006)
5. Which one of the following is not a second messenger in hormone action?
(a) cAMP (b) cGMP
(c) Calcium (d) Sodium
(AIPMT 2006, WB JEE 2011)
6. Which of the following statements regarding glucagon is false?
(a) It is secreted by a-cells of Langerhans.
(b) It acts antagonistically to insulin.
(c) It decreases blood sugar level.
(d) The gland responsible for its secretion is heterocrine
gland. (AIIMS 2007)
7. LH and FSH are collectively called
(a) somatotrophins (b) oxytocin
(c) gonadotrophins (d) luteotrophic.
(BHU 1993, 2006, UP-CPMT 2008)
8. Progesterone hormone is secreted by which of the following glands ?
(a) Corpus luteum
(b) Hypothalamus
(c) Mature Graafian follicle
(d) Pituitary
(BHU 2003, 2007)
9. Which one of the following hormones never reaches cytoplasm?
(a) Estrogen (b) FSH
(c) Progesterone (d) Testosterone
(BHU 2008)
10. Antidiuretic hormone is also known as
(a) secretin (b) vasopressin
(c) gastrin (d) renin.
(UP-CPMT 2009)
11. During emergency, which one of the following hormone is important?
(a) Aldosterone (b) Adrenaline
(c) Thyroxine (d) Calcitonin
(UP-CPMT 2000, 2008, BHU 2006)
12. Which is responsible for sleep wake cycle movement?
(a) Dopamine (b) Melatonin
(c) Serotonin (d) Adrenaline
(AMU 2006, Kerala 2010, AIPMT Mains 2011)
13. Rapid increase in the blood sugar level of a patient can be immediately reduced by
(a) injecting insulin intravenously
(b) injecting insulin intramuscularly
(c) administering glucagon intravenously
(d) consuming large quantities of insulin tablets.
(Karnataka 2008)
14. Which of the following hormones is steroid ?
(a) Epinephrine (b) Thyroxine
(c) Estrogen (d) Gonadotropin
(Odisha 2007,2009)
15. Diabetes mellitus is caused due to deficiency of
(a) glucose (b) vasopressin
(c) insulin (d) glucagon.
(Odisha 2009,2012)
16. Diabetes insipidus is due to the insufficient release of
(a) insulin (b) glucagon
(c) ADH (d) thyroxine.
(UP-CPMT 1996,1999, AIIMS 1994, AMU 2011)
17. Erythropoietin is secreted from
(a) pituitary gland (b) pancreas
(c) adrenal gland (d) kidney. (J & K 2011)
18. Given below is an incomplete table on hormones, their source glands and one major effect of each human body. Identify the option representing correct grouping of hormone, its gland and effect.

Gland Secretion Effect on Body
A Oestrogen Maintenance of secondary sexual characters
Alpha cellsof Islets of Langerhans B Raises blood sugar level
Anterior pituitary C Over secretion leads to gigantism
(a) Ovary Glucagon Growth hormone
(b) Placenta Insulin Vasopressin
(c) Ovary Insulin Calcitonin
(d) Placenta Glucagon Calcitonin

(AIPMT Prelims 2011)

19. You met a person who has bulging/protruding eyes, tachycardia and higher body temperature. He suffered from
(a) hyperthyroidism (b) acromegaly
(c) diabetes (d) cretinism.
(AIIMS 2000)
20. Which one of the following pairs of hormones are the examples of those that can easily pass through the cell membrane of the target cell and bind to a receptor inside it (mostly in the nucleus)?
(a) Insulin, glucagon
(b) Thyroxine, insulin
(c) Somatostatin, oxytocin
(d) Cortisol, testosterone. (AIPMT Prelims 2012)
21. What is correct to say about the hormone action in humans?
(a) Glucagon is secreted by p—cells of islets of Langerhans and stimulates glycogenolysis.
(b) Secretion of thymosins is stimulated with aging.
(c) In females, FSH first binds with specific receptors on ovarian cell membrane.
(d) FSH stimulates the secretion of estrogen and progesterone.
(AIPMT Prelims 2012)
22. Choose the mismatched pair from the following.
(a) Insulin – Gluconeogenesis
(b) Glucagon – Glycogenolysis
(c) Oxytocin – Contraction of uterine muscles
(d) Prolactin – Milk production in mammary glands
(Karnataka 2012)
23. Which of the following is a mixed gland ?
(a) Thyroid gland (b) Adrenal gland
(c) Pituitary gland (d) Pancreas
(Odisha 2012)
24. From which cell of islets of Langerhans, is insulin secreted?
(a) Alpha cells (b) Delta cells
(c) Beta cells (d) All of these
(DPMT 1995, UP-CPMT 1996, Odisha 2012)
25. Which of the following hormones has no effect on heart beat?
(a) Thyroxine (b) Oxytocin
(c) Adrenaline (d) Noradrenaline
(AFMC 2012)
26. The cancer arising in C cells of thyroid gland is called

(a) papillary cancer (b) medullary cancer
(c) anaplastic cancer (d) follicular cancer.
(AFMC 2012)
27. The heart beat increases at the time of interview due to
(a) secretion of adrenaline
(b) corticotrophic hormone
(c) hypersecretion of renin
(d) autidiuretic hormone secretion.
(AIIMS 1999, BHU 2012)
28. Select the option which correctly matches the endocrine gland with its hormone and its function.

Endocrine Hormone Function
(a) Placenta Estrogen Initiates secretion of
the milk
(b) Corpus Luteum Estrogen Essential for maintenance of endometrium
(c) Leydig’s cells Androgen Initiates the production
of sperms
(d) Ovary FSH Stimulates follicular
development and the secretion of estrogens

(NEET – Karnataka 2013)

29. Select the answer which correctly matches the endocrine gland with the hormone it secretes and its function/ deficiency symptom.

Hormone Function/Deficiency
(a) Thyroid gland Thyroxine Lack of iodine in diet results in goitre
(b) Corpus
Testosterone Stimulates
(c) Anterior
Oxytocin Stimulates uterus contraction during child birth
(d) Posterior
Over secretion simulates abnormal growth

30. Identify the hormone with its correct matching of source
and function.
(a) Oxytocin – posterior pituitary, growth and maintenance of mammary glands.
(b) Melatonin – pineal gland, regulates the normal rhythm of sleepwake cycle.
(c) Progesterone – corpus luteum, stimulation of growth and activities of female secondary sex organs.
(d) Atrial natriuretic factor – ventricular wall, increases
the blood pressure. (AIPMT 2014)

Assertion and reason based questions

The following questions consist of two statements each : assertion (A) and reason (R). To answer these questions, mark the correct alternative as directed below:
(a) If both A and R are true and R is the correct explanation of A.
(b) If both A and R are true but R is not the correct explanation of A.
(c) If A is true but R is false.
(d) If both A and R are false.
1. Assertion: Diabetes insipidus is marked by excessive urination and too much thirst.
Reason : Antidiuretic hormone is secreted by the posterior lobe of pituitary gland.
2. Assertion: Glucagon is said to lower down the blood sugar level.
Reason: Glucagon increases the utilisation of glucose in the tissues and the synthesis of liver glycogen.
3. Assertion : Excessive amounts of calcitonin in the blood causes softening of bones.
Reason : Calcitonin causes mobilisation of calcium from the bones to the blood plasma.
4. Assertion : Immunity theory of ageing is associated with thymus gland.
Reason : Thymosin hormone is responsible for maturation of lymphocytes.
5. Assertion : Erythropoietin hormone is secreted from kidney in oxygen shortage conditions.
Reason : Erythropoietin stimulates the bone marrow to increase the production of RBCs.
6. Assertion : T4 is converted to T3 by removal of one iodine in the liver, kidney and some other tissues. Reason : T4 is secreted in smaller amounts but it is more active and several times more potent than T3.
7. Assertion : In exophthalmic goitre, there is excessive secretion of thyroid hormone.
Reason : Thyroid gland enlarges in exophthalmic goitre.

1. Fill in the blanks.
(i) ________regulate the development, maturation
and functions of male accessory sex organs.
(ii) The hormone________is a modified amino
(iii) Hormone secreting cells called neurosecretory cells,
are abundant in the________.
(iv) All the pituitary hormones are molecules made
chiefly of monomers of________.
(v) All the hormones of adrenal cortex are synthesized
2. Name the four tropic hormones secreted by anterior pituitary and the respective hormones released by them.
3. Why injury to adrenal cortex is not likely to affect the secretion of adrenaline?
4. Which type of hormones control the menstrual cycle in human beings and how?
5. If hormone receptor molecules are removed from target organs then what will happen?


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