One of the most common skin disorders, which affects about 22% of the world population is atopic dermatitis. This is a rather complex disease neurogenic-allergic nature with a characteristic undulating course where the periods of exacerbations replace remission. Often it leads to temporary disability and may even cause disability.
Typically, the disease affects a person in the first year of life, with 70% of patients in the immediate family has a history of allergic rhinitis, hay fever or asthma.
With the development of the disease on the smooth skin rashes occur in characteristic form of nodular elements, accompanied by intense itching, they tend to merge with the formation of foci of infiltration and lichenification.
Typically, atopic dermatitis occurs in the form of attacks, suddenly appearing on the background of relative calm. In some cases, such a state can provoke allergies to pollen of various plants. Allergens contained in the cluster of pollen grains of seed plants, can affect not only the mucous membranes of the eyes and respiratory tract, but also cause various skin manifestations. Spring allergies can cause the development of the pollen of shrubs and trees, in summer – cereals, and in the autumn – the pollen of weeds. In clinical practice, pathological state with clearly repeating the season, which is caused by pollen and is accompanied by acute inflammatory lesions covering tissue is called hay fever. As a rule, the severity of the disease depends on the degree of pollen sensitization, as well as concomitant pathologies and allergic reactions. This explains the fact that people suffering from neurodermatitis, relapses occur against the background of acute pollinosis.
Note that pollinosis – a disease which has several clinical forms, depending on the severity and localization of the pathological process. It can not only cause allergic skin reactions, but also the destruction of the mucous membranes. The fact that the pollen can simultaneously be 5-10 antigenic components. Components that are part of the water-soluble fraction of pollen antigen of the mucous membranes, and those that are included in the liposoluble fraction provoke the development of allergic skin reactions.
As a result, the skin barrier function is disrupted, the sweat and sebaceous glands, increased evaporation of moisture from the surface of the stratum corneum and in the skin is reduced lipid content. Also, very often due to changing neurodermatitis skin pH and alkalinity in the direction of reducing the amount of immunoglobulin class biocenosis changes of the skin, and therefore the factors of allergic inflammation can join fungal and microbial antigens.
During exacerbation of the pathological process of the skin starts to peel off and on its surface there are blisters. Patients torments intolerable itch, however, combing the skin, they thereby only exacerbating an already difficult situation.
However neurodermatitis can trigger the development of family history, a violation of the functional state of the immune system and metabolism, malfunction of the CNS and internal organs. Also aggravate the disease can negative emotions, stress and depression. That is why before starting the treatment of neurodermatitis, you need to find the true cause of the disease.