The parasite responsible for Malaria – Plasmodium

Members of the genus Plasmodium are collectively known as malarial parasites. They cause a febrile disease called malaria. Malaria as achill and fever disease is known to mankind for a long time. Eradication of malaria is an important problem in public health. For a long time it was believed that malaria was caused by harmful vapours produced in marshy land (Gr. Malo-bad+air).

PlasmodiumCharles Laveran, a french military surgeon, for the first time, noticed Plasmodium in the blood of a malarial patient, in 1880. Its connection with the intermediate host and the modes of transmission were experimentally worked out in Calcutta by Sir Ronald Ross in 1889. For this discovery he was awarded the nobel prize for medicine in 1902. Grassi (1890) provided absolute scientific proof for the specific relationship between Anopheles mosquito and the human malarial parasite.

The plasmodium

It is an intracellular sporozoan blood parasite. For the completion of life cycle it requires two hosts, a vertebrate and a blood sucking invertebrate. Transference of the parasite is effected by the invertebrate host. In man, the infection takes place by the inoculation of the slender, sickle shaped nucleated sporozoite in the blood by the bite of an infected female mosquito belonging to the genus Anopheles.

At least four species of Plasmodium:

P. vivax, P. falciparum, P. malariae and P. ovale, are known to attack man causing different kinds of malaria. The life cycle of the malarial parasite involves two hosts, the man and the mosquito. The modes of development in these two hosts are different. In man the mode of reproduction is asexual and in mosquito it is sexual. Man is the intermediate host and the mosquito is the definitive host.

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Comments ( 7 )
  1. Life Cycle of Plasmodium in Man – Schizogony | Hourly Book
    July 16, 2012 at 11:48 am

    […] are two phases in the life cycle of malarial parasite in man.They […]

  2. renato
    January 6, 2013 at 6:51 pm

    Great article!!

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    January 9, 2013 at 2:18 pm

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  4. sarun magar
    January 13, 2013 at 11:43 am

    this is good article.

  5. crystal lara
    January 14, 2013 at 7:39 am

    WOW !! This is a very interesting article.. I learned something new .

  6. Samuel Livingston
    January 16, 2013 at 2:50 am

    This is amazing! Great article!

  7. darps
    January 20, 2013 at 7:17 am

    hi very informative for a medical related courses.. keep it up

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